PUO: Can it be anti synthetase syndrome

Abstract

Anti-synthetase syndrome is a set of clinical features with presence of specific anti synthetase antibodies. Presentation varies from patient to patient and symptoms can develop at varying course of the disease. Unexplained fevers with no other set of symptoms can be a presentation, so patients presenting with pyrexia of unknown origin should be evaluated for the presence of anti-synthetase syndrome as early diagnosis is must both for therapeutic and prognostic factors.