Risk Factors for Predicting Mortality in a sick children in Paediatric Intensive Care Unit in developing country

Abstract

Aim: The aim of this study is to assess risk factors contributing to increased mortality and their association with PRISM III 24 hour score in PICU. Materials and Methods: In this observational prospective study, 200 children admitted fulfilling inclusion criteria during 24 months period were enrolled in this study. PRISM III-24 score and mortality risk factor were calculated. Follow up was noted as discharge or death. Result: of 200 patients 115 male and 85 female.45 died and155 survived. PRISM III-24 score showed an increase of mortality from 4% in 0-9 score patients to 83.3% in ≥ 30 score. The presence of GCS score ≤ 8,MODS on admission ,need of inotropes and mechanical ventilation was significantly associated with poor outcome and well correlated with PRISM III score on univariate linear regression analysis. MODS on admission,mechanical ventilation and need of inotropes are independant predictors for PICU mortality on multiple logistic regression analysis. Conclusion: GCS score ≤ 8 ,MODS on admission ,need of inotropes and mechanical ventilation was significantly associated with poor outcome and well correlated with PRISM III-24 score. High PRISM III -24 score, MODS on admission ,mechanical ventilation and need of inotropes are independant predictors for PICU mortality.