Association of metabolic syndrome with psoriasis: a hospital based cross-sectional study

Abstract

Background: Psoriasis is associated with significant morbidity which may have a significant impact on the quality of life of patients even if a relatively limited body surface area is involved.Aims: The present study was aimed to assess the association of psoriasis and metabolic syndrome and to evaluate the disease activity and duration in psoriatic patients with and without metabolic syndrome.Materials and Method: 85 psoriasis subjects without prior systemic treatment for 1 month were included. A complete lipid profile with fasting blood glucose levels, blood pressure, and central obesity were assessed and the results were formulated. Results: 33 out of 85 patients had metabolic syndrome. Impaired HDL levels and fasting triglyceride of metabolic syndrome seen in 60% and 55.2% respectively. Metabolic syndrome and the extent of body surface area involved by psoriasis were directly associated. Patients with psoriasis of more than 72 months had more metabolic syndrome (37.84%). There was no significant correlation between PASI score and metabolic syndrome. Conclusion:The present study concludes that there exists an association between psoriasis and metabolic syndrome. This has important implications in dermatology to prevent associated serious complications.