Status of Clinico-pathological Study of Uterine Leiomyomas in Hysterectomy Specimens in a Tertiary Care Teaching Hospital

Abstract

Background: Uterus is the vital reproductive organ of female which is hormone responsive. Myometrium is the thick, smooth muscle coat of the uterus underneath the endometrium and is covered by the peritoneum derived serosa. Subjects and Methods: Total of sixty-seven hysterectomy specimens with or without salphingo-oophorectomy diagnosed clinical and radiologically as uterine leiomyomas were subjected to examination. Brief patient’s clinical data was retrieved with respect to age, parity, clinical manifestation, sonographic findings and basis of diagnosis. Results: The most common indication of hysterectomy between the study period was uterine fibroid being 53.7% followed by pelvic organ prolapse constituting 28.4%. Majority of leiomyomas were diagnosed in multiparous women. Out of 67 patients with leiomyomas, 58 (86.6%) were multiparous, which includes 7(10.4%) cases of uniparous patients and only 2 was nulliparous (3.0%). Conclusion: Fibromyoma is the most common benign tumor of the pelvis. It commonly affects the women of child-bearing age, mostly in the third decade. The most common mode of presentation is menstrual disturbances. Intramural fibroid is the most common variety. The proliferative endometrium, followed by secretary endometrium was commonly reported.