A study of Revisiting Dyslipidemia in Stroke in tertiary care center in South India

Abstract

Background: Atherosclerosis affects multiple vascular beds, accounting for some proportion of ischemic strokes. Serum lipid levels have an effect on the short-term mortality due to strokes. But in some studies, there was no dyslipidemia in patients who presented to the hospital with acute stroke. It is important to evaluate the serum lipid levels in both types of strokes to guide lipid lowering therapy which can reduce incidence of stroke and related mortality. This study is done to evaluate the role of serum lipids in patients of stroke in our centre. Methods: It is a cross sectional study, conducted on 176 patients of stroke, who were assessed with NIHSS stroke scale clinically. Serum lipid profile was measured in all the patients. Data was entered in Microsoft Excel and analysed by descriptive statistics. Chi Square test was used for association of qualitative variables. A p value<0.05 was considered statistically significant. Results: In this study conducted on 176 patients, LDL values were deranged more in CVA-patients with bleed, group compared to CVA-infarct group. BMI was the best anthropometric measure that correlated well with LDL. LDL was the most common parameter deranged in nonsmokers (61.8%) whereas in smokers, total cholesterol (66.3%) was most commonly deranged. Triglyceride and VLDL values were deranged more commonly in the diabetic group than in the non-diabetic group. A total of 123 out of 145 patients CVA with infarct, had deranged lipid profile and among patients CVAwith bleed 24 out of 32 had deranged lipid profile. Conclusions: The Result of this study shows significant derangement in lipid profile especially inLDL cholesterol levels in both infarct and bleed group, therefore starting statin therapy would prove to be useful in preventing recurrence of stroke.