A Hospital Based Prospective Study to Evaluate the Risk Factors of Uveitis in Ankylosing Spondylitis at Newly Established Tertiary Care Centre

Abstract

Background: Ankylosing spondylitis (AS) is a chronic, inflammatory disease of the axial spine that can manifest with various clinical signs and symptoms. The present study was conducted in the Department of Orthopedics, Government Medical College, Barmer, Rajasthan, India with the aim ofevaluating the risk factors of uveitis in Ankylosing spondylitis. Materials &Methods: A total of 50 AS patients were enrolled. Complete demographic and clinical data of all the subjects was obtained. The diagnosis of uveitis is performed by ophthalmologists. Through clinical and medical examination of all the subjects was carried out. Blood samples were obtained and biochemical profile was assessed. Statistical analysis was done by SPSS software. Results: Prevalence of uveitis was 16 percent. Non-significant results were obtained while comparing the mean AST and ALT levels among uveitis and non-uveitis patients. Mean uric acid level among the patients of uveitis group was significant higher in comparison to non-uveitis group. Mean circulating immune complexes among the patients of uveitis group was significant higher in comparison to non-uveitis group. Conclusion: From the above results, the authors concluded that hip involvement and serum uric acid and immune complexes might be associated with higher rates of uveitis in AS.