Seroprevelence of transfusion transmissible infection at regional blood transfusion center Government General Hospital/Government Medical College, Nalgonda 2018-2020

Abstract

Background: Blood Transfusion is the integral part of modern medicine and surgical procedures. Blood transfusion saves many people every year that would otherwise have died because of various natural diseases and disasters. But unsafe blood transfusion has the potential to transmit a diverse of infections to blood recipients. These infections could be due to viruses, bacteria, protozoans, and/or prions. Viral agents include human immunodeficiency virus (HIV), Hepatitis B virus (HBV) and Hepatitis C virus (HCV)[1,2]. HIV, HCV, HBV and VDRL are preventable diseases. A fundamental part and priority transfusion transmitted infections is to notify and counsel reactive donors. To prevent secondary transmission of infectious disease. Method: ELISA is highly sensitive and specificity test. All the blood units screened for ELISA which is superior compared to the rapid method detection. Results: 5423 units of samples were screened 61 were reactive among these HIV(8), HBSAG(50), HCV(2), VDRL(1). Conclusion: The decrease in prevalence and trends of TTIS among the study donors demonstrated the safety measures which were employed in the recent years were effective. ELISA is the time saving and gold standard method for screening of blood donor units.