Assessment of Microbial Profile and its Usefulness in Indian Females with Symptomatic Vaginal Discharge

Abstract

Background:Vaginal discharge in females can be normal and physiological that changes with the menstrual cycle. Pathologic Vaginal discharge leads to significant morbidity in young age group females. Aims: The present clinical trial was carried out to evaluate the symptomatic vaginal discharge incidence in females of different age groups and to assess microbiological profile in females with symptomatic vaginal discharge. Materials and Methods: In 80 females, vaginal swabs were collected for the microbiological evaluation followed by Wet mount preparation and Nugent’s scoring system for microbial assessment.The collected data were subjected to the evaluation for results formation. Results: Nugent scores showed that 43.75% (n=35) females had bacterial vaginosis, Trichomonas, pus cells, and clue cells were respectively seen in 41.25% (n=33), 21.25% (n=17), and 8.75% (n=7) subjects. For vaginal candidiasis, two species seen were Candida parapsilosis and Candida Albicans which were respectively isolated from 17 (94.4%) and 2 (5.5%) subjects of vaginal candidiasis. Other organisms isolated and identified in study females were Staphylococcus Aureus, Pseudomonas Aeruginosa, E Coli, Coagulase Negative Staphylococcus, Enterococcus, Klebsiella, and Acnitobacter isolated from 8, 2, 19, 2, 12, 1, and 3 subjects respectively. Conclusion:Pathologic and excessive vaginal discharge in females can lead to significant morbidity, discomfort, and financial constraints in healthy females and require early diagnosis and microbial detection to ensure effective treatment modality.