Comparison of Vitamin D status in postmenopausal women with and without hypothyroidism

Authors

  • Anoop Singh Gurjar Associate Professor, Department of Anatomy, Government Medical College, Pali, Rajasthan, India.
  • Manisha Gurjar Associate Professor, Department of Biochemistry, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.
  • Vasudev Sankhla Senior Demonstrator, Department of Biochemistry, Government Medical College, Pali, Rajasthan, India

Abstract

Background: Menopause comes with a number of health challenges for women. In its postmenopausal phase woman is not only facing the deficiency of ovarian hormones, she is also at risk of developing hypothyroidism and hypovitaminosis D.  Objectives: The present study was therefore planned with an aim to determine and compare the mean vitamin D levels among postmenopausal women with and without hypothyroidism to evaluate if hypothyroidism in post-menopausal women affects the vitamin D levels. Material & Methods: The present study was conducted in Department of Biochemistry, Dr. S. N. Medical College, Jodhpur, Rajasthan, India after obtaining the Ethical approval from the Institutional Ethics Committee. Post-menopausal women above 50 years of age attending the medical OPD with the symptoms suggestive of hypothyroidism were included. Those currently on medication for thyroid disorders and on Vitamin D supplementation for past six months were excluded. The subjects were divided into two groups based on their thyroid levels into Case group (S.TSH >5.60µIU/ml) and Control group (S.TSH: 0.34-5.60 µIU/ml) Results: Mean serum Vitamin D level was significantly lower in Case Group (17.33±16.67 ng/ml) as compared to Control Group (27.55±15.82 ng/ml). More number of hypothyroid subjects were Vitamin D deficient (Case Group-36%) as compared to Control Group (12%). Pearson correlation coefficient was also assessed between Vitamin D and TSH level (r value -22.52) and no association was observed among the two parameters in Case Group.Conclusions: Patients with hypothyroidism also suffers from hypovitaminosis D. Screening of postmenopausal women for hypothyroidism and Vitamin D levels is recommended.

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Published

2021-11-21

How to Cite

Anoop Singh Gurjar, Manisha Gurjar, & Vasudev Sankhla. (2021). Comparison of Vitamin D status in postmenopausal women with and without hypothyroidism. International Journal of Health and Clinical Research, 4(20), 425–427. Retrieved from https://www.ijhcr.com/index.php/ijhcr/article/view/3313