Study of carotid intima media thickness and lipid profile in cases of ischaemic stroke

Abstract

Background: Stroke is one of the leading reasons for mortality throughout the world. Measurement of carotid intima media thickness (CIMT) is a reliable marker for the development of atherosclerosis and ischemic stroke (IS). Aims: To study the carotid Intimal-medial thickness in patients with Ischemic stroke proven by computed tomography or MRI. To study the correlation between the increase in carotid artery intimal medial thickness & dyslipidemia in patients with ischemic stroke proven by computed tomography or MRI. Materials and methods: Our study is a cross-sectional study of hundred patients, Hundred patients admitted with acute ischemic stroke confirmed by computer tomography (CT)/MRI admitted in our Hospital. The blood collected within 24 hrs of admission for lipid-profiles. eg., sr. cholesterol, TG, HDL, LDL, VLDL. Carotid Doppler study in patients of ischemic stroke. Patients, who met the inclusion-criteria, are included in the study. Results: A total of 144 patients were screened in 81% patients with CT proven ischemic stroke, there is an increase in intimal- medial thickness of common carotid-internal carotid artery. A statistically significant correlation was found between increased intimal-medial thickness in patients of ischemic stroke and abnormal triglycerides & HDL. Conclusion: CIMT measurement and lipid profile can be used as primary preventive measure for prediction of stroke in elderly population.