Study of Prostatic Lesions in Tertiary Care Hospital In Konakan Region: Histomorplogical Lesions

Abstract

Background: Prostate gland isinvolved in three pathologic processes namely prostatitis, nodular hyperplasia and carcinoma. The important causes for prostatic morbidity and mortality are inflammation, nodular enlargement and tumours. BPH is a part of normal ageing process affecting 210 million males worldwide.BPH is the most common urologic disorder in men beyond 40 years of age group and is almost present in men aged 80-90 years of age group. Furthermore, prostatic tumoursare a very important cause of male morbidity and mortality and prostate cancer is second only to lung cancer among cancer-related deaths in men. Objective: To study prevalence and incidence of various morphologic types of prostatic lesions in tertiary care hospital in Konkan region. Materials and Methods: The present study was carried out in the Department of Pathology at Dervan, Sawarde for two year period from 1st Jan 2019 to 31st Dec 2020. The prostatic tissues bits/ biopsies received at the Pathology Department were included in the study. Results: A total of 76 cases were included in the study. BPH was diagnosed in 60 patients while malignancy was diagnosed in 16 patients. Two patients had previous history of prostatic carcinoma and presented with metastatic disease at the time of the study. Conclusion: BPH is commonest lesion in advancing age however continuous monitoring of symptomatic patient is necessary with advancing age. The PSA Values above 20.1ng/ml are significantly correlated to prostatic carcinoma.