Association of lipid profile in migraine and non- migraine patients: an observational study
Keywords:
Migraine, Lipid profile, Cholesterol, Dyslipidemia, StrokeAbstract
Introduction Migraine is one of the commonly encountered conditions in medical practice. It is a complex syndrome with many symptoms and manifestations. Migraine is defined as a moderate to severe headache lasting four to 72 hours, usually preceded by a prodromal period of depression, irritability, restlessness, anorexia and often associated with an aura. It may be visual, somatosensory and motor in nature. It is of special interest to ophthalmologists because migraine is often associated with visual symptoms and at times can even be alarming. Dyslipidemia is one of the possible risk factor in patients of migraine and having increase risk of coronary vascular disease. Due to the high prevalence of migraine in India, studies should be performed to turn attention to this issue, which has been neglected so far.Materials and Methods The present study was conducted in the Department of Ophthalmology at Muzaffarnagar Medical College and Hospital from October 2018 to April 2020. A total of 525 patients were included in this study, out of which 325 patients were taken as control having no significant complain under group A and 200 patients having migraine were taken as cases under group B.Results Serum Total cholesterol (>170mg/dL), LDL (>100mg/dL), HDL (<45mg/dL) and Triglyceride (>150mg/dL) was reported among 68.5%, 61.5%, 25.5% and 21% of the subjects respectively in group B, while the same was revealed in 9.54%, 6.77%, 5.23% and 3.69% of the subjects respectively in group A.Conclusion: This study found a significant association between migraine and deranged lipid profile.