Obstructive sleep apnea in patients with interstitial lung diseases

Abstract

Background: Interstitial lung diseases (ILD) are a heterogeneous group of diffuse parenchymal lung disorders with highly variable clinical courses and outcomes pulmonary fibrosis. The present study was conducted to assess cases of Obstructive sleep apnea (OSA) in patients with interstitial lung diseases (ILD). Materials & Methods: 58 patients of ILD of both genders were assessed for pulmonary function testing, forced expiratory volume in one second, and forced vital capacity (FVC), arousal index, AHI index, arousal index and desaturation index. Results: Interstitial lung diseases were IPF seen in 22 in OSA group and 25 in no OSA group, NSIP seen in 4 in each group and CTD seen in 2 in OSA group and 1 in no OSA group. Pulmonary function showed FVC (%, predicted) as 75.2 and 70.5, FEV1 (%, predicted) as 85.2 and 77.3, DLco (%, predicted) as 58.6 and 52.6. Six-minute walk test distance (m) was 382.3 and 332.8 and initial SpO2 (%) as 95.4 and 95.0. AHI index was 17.6 and 2.5, desaturation index was 11.2 and 1.6, arousal index was 12.5 and 8.4, longest apnea was 36.4 and 17.6 and snoring was 3.8 and 4.7 in OSA and no OSA group. The difference was significant (P< 0.05). Conclusion: Interstitial lung disease patients exhibited high cases of obstructive sleep apnoea.